MOLAMINE™ TRIS

Tromethamine

(Buffering Agent / Stabilizer)

tromethamine-bp
MOLAMINE™ TRIS is an organic compound, widely recognized as Tromethamine. This carefully crafted white crystalline powder is a key excipient in various pharmaceutical formulations. It is primarily used as a buffering agent and stabilizer.

MOLAMINE™ TRIS

by Muby Chem

tromethamine

Tromethamine

Muby Chem operates a state-of-the-art manufacturing facility producing Tromethamine, known for its exceptional purity and efficacy. It is widely used in pharmaceutical industry.

Our advanced technology ensures uniformity and consistency in the formulation of    Tromethamine, making it a reliable and effective material in various pharmaceutical industry.

Application: MOLAMINE™ TRIS serves as an essential biological buffer in the pH range of 7.0 to 9.0, stabilizing vaccines, parenteral (injectable) solutions, and protein-based biologics. In injectable medication, it functions directly as a proton acceptor to prevent and correct metabolic acidosis during cardiac bypass surgery or cardiac arrest.

We follow Good Manufacturing Practices (GMP) and adhere to international regulatory standards to ensure quality consistency with continuous supply.

MOLAMINE™ TRIS TYPICAL PROPERTIES

#PROPERTYTYPICAL VALUE
1 CAS No 77-86-1
2 Molecular Formula C4H11NO3
3 Molecular Weight 121.1 g/mol

SPECIFICATION

#TESTSPECIFICATION - BP
1 Appearance It occurs as a white or almost white, crystalline powder, or colorless crystals.
2 Identification
Test (A)
Test (B)
Test (C)
Test (D)
(A) The solution is strongly alkaline.
(B) Melting point: 168℃ to 174℃.
(C) Infrared absorption spectrophotometry.
(D) Examine the chromatograms.
3 Solubility It is freely soluble in water, sparingly soluble in ethanol (96 per cent), very slightly soluble in ethyl acetate.
4 Appearance of solution The solution is clear and colorless.
5 pH Between 10.0 to 11.5.
6 Related substances Not more than 1.0%.
7 Chloride Not more than 100 ppm.
8 Iron Not more than 10 ppm.
9 Loss on drying Not more than 0.5%.
10 Sulfated ash Not more than 0.1%.
11 Assay Not less than 99.0% and not more than 100.5% of aminomethylidynetri(methanol), dried substance.

PACKAGING                                                                                                                

MOLAMINE™ TRIS is packed in HDPE bag or drum with double PE liners inside having bar-coded label and tamper-evident seal.

SHELF LIFE, STORAGE AND PACKING

The shelf life is 3 years. It is preserved in tight containers.

ACCREDITATIONS

fda
health canada
edqm1
edqm
sgs
ANVISA
sfda
saphra
tga
china
mhra
cdsco
who
eu
exci
ecovadis

Disclaimer

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